DNA
Book Review: The Making of the Fittest: DNA and the Ultimate Forensic Record of Evolution by Sean Carroll


(out of 5 stars)
Molecular biologist Sean Carroll presents an outstanding, deeply scientifically satisfying look at the forensic evidence for evolution in The Making of the Fittest. By focusing his argument on the very smallest bits of evidence, Carroll provides an amazing look into the world of the cell and DNA which leaves the reader with little doubt that evolution and natural selection are clearly capable of developing the entities and processes we find in nature today.
Starting off with a look at bloodless cold-water fish, Carroll jumps into the nature of adaptive mutations. Moving on, he shows that, given time and large numbers, the "miracles" of evolution are practically inevitable, even if not specifically predictable in every detail. Carroll demonstrates that some genes are nearly "immortal", lasting nearly unchanged for millions of years. Further, he explores how old genes and their proteins are frequently repurposed into new uses.
From there, the book moves into fossil genes which allow researchers to trace changes in lineages, as well as the fact that evolution tends to favor the production of similar results even if the affected genomes are not related. Carroll wraps up by showing that humans and other complex entities can be produced by the power of DNA, natural selection, mutation, and drift.
A great follow up to Carroll's previous work on evolutionary development, Fittest is a fascinating glimpse into the world of microbiological detectives. Highly recommended to anyone with an interest in biology and evolution. Four and one-half stars.














































